Biological Nitrogen Removal Database

A manually curated data resource for microbial nitrogen removal

Detailed description of the enzyme

Enzyme name	Nitrite reductase (NO-forming)
Synonyms	Dissimilatory nitrite reductase; Copper-containing dissimilatory nitrite reductase; Copper-containing nitrite reductase; Cu-NirK; Cu-NIR; Cu-NirK; Nitrite reductase; nirK; Periplasmic nitrite reductase;
Gene cluster	ncgABCnirK
Classification	Oxidoreductases
Genes	nirK, nirS
Pathway	Nitrogen metabolism: Denitrification: Nitrite reduction
Substrate	Nitrate Quinol
Product	Nitrite Ferrocytochrome C Hydron
Mechanism	Link
Subunit
Gene Protein name Organism Status Accession Number (Genbank) Accession Number (GenPept) Accession Number (UniProt)	nirK Copper-containing nitrite reductase Alcaligenes faecalis Reviewed D13155 BAA02440.1 P3850
Reference
Authors Title PubMed ID Full research link	Bueno et al., 2005 Function of the Rhizobium Etli CFN42 nirK Gene in Nitrite Metabolism 15667294 Link
Authors Title PubMed ID Full research link	Nakanishi et al., 2010 A Eukaryotic Copper-Containing Nitrite Reductase Derived From a NirK Homolog Gene of Aspergillus Oryzae 20460712 Link
Authors Title PubMed ID Full research link	Gao et al., 2017 Cloning, Purification and Characterization of Novel Cu-containing Nitrite Reductase From the Bacillus Firmus GY-49 29255935 Link
Authors Title PubMed ID Full research link	Glockner et al., 1993 Copper-containing Nitrite Reductase From Pseudomonas Aureofaciens Is Functional in a Mutationally Cytochrome cd1-free Background (NirS-) of Pseudomonas Stutzeri 8352648 Link
Authors Title PubMed ID Full research link	Adhikari and Rahman., 2017 Comparative Analysis of Amino Acid Composition in the Active Site of Nirk Gene Encoding Copper-Containing Nitrite Reductase (CuNiR) in Bacterial Spp 28068515 Link
Authors Title PubMed ID Full research link	Beaumont et al., 2005 Novel nirK cluster genes in Nitrosomonas europaea are required for NirK-dependent tolerance to nitrite 16166549 Link