Biological Nitrogen Removal Database

A manually curated data resource for microbial nitrogen removal


Detailed description of the enzyme

Enzyme name Methyl coenzyme M reductase
Synonyms MCR;methyl coenzyme M reductase A;methyl coenzyme M reductase;mcrA;
methyl-CoM reductase;methyl-coenzyme M reductase A;MCR I;
MCR II alpha;MCR II beta;MCR II gamma
Gene cluster mcrABG
Classification Transferases
Genes mcrA;mcrB;mcrG
Pathway Nitrogen metabolism: nitrite-dependent anaerobic methane oxidation (N-DAMO): Methanogenesis
Substrate methyl-CoM;Coenzyme B
Product Methane;Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfide
Mechanism Link
Subunit
Gene
Protein name
Organism
Status
Accession Number (Genbank)
Accession Number (GenPept)
Accession Number (UniProt)
mcrA
methyl-coenzyme M reductase alpha subunitĀ 
Methanothermobacter thermautotrophicus strain Marburg
Reviewed
X07794
CAA30639.1
P11558
Reference

Authors

Title

PubMed ID

Full research link

Shima and Thauer. 2005

Methyl-coenzyme M reductase and the anaerobic oxidation of methane in methanotrophic Archaea

16242993

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Authors

Title


PubMed ID

Full research link

Zhu et al., 2019

Nitric Oxide Dismutase (nod) Genes as a Functional Marker for the Diversity and Phylogeny of Methane-Driven Oxygenic Denitrifiers

31354671

Link

Authors

Title


PubMed ID

Full research link

Wu et al., 2011

A new intra-aerobic metabolism in the nitrite-dependent anaerobic methane-oxidizing bacterium Candidatus 'Methylomirabilis oxyfera'

21265781

Link

Authors

Title


PubMed ID

Full research link

Zhu et al., 2017

Unexpected Diversity and High Abundance of Putative Nitric Oxide Dismutase (Nod) Genes in Contaminated Aquifers and Wastewater Treatment Systems

27986721

Link