Biological Nitrogen Removal Database

A manually curated data resource for microbial nitrogen removal


Detailed description of the enzyme

Enzyme name Hydrazine synthase
Synonyms Ammonium;
Nitric oxide;
Ferrocytochrome c;
Gene cluster hzsABC
Classification Oxidoreductases
Genes hzsA, hzsB, hzsC
Pathway Nitrogen metabolism: Anaerobic ammonium oxidation: Condensation of
nitric oxide (NO) with ammonium to form hydrazine
Substrate Ammonium
Nitric oxide
Ferrocytochrome c
Product Hydrazine 
Ferricytochrome c
Water
Mechanism Link
Subunit
Gene
Protein name
Organism
Status
Accession Number (Genbank)
Accession Number (GenPept)
Accession Number (UniProt)
hzsA (kuste2861)
Hydrazine synthase subunit alpha
Kuenenia stuttgartiensis
Reviewed
CT573071 
CAJ73613.1
Q1Q0T2
Gene
Protein name
Organism
Status
Accession Number (Genbank)
Accession Number (GenPept)
Accession Number (UniProt)
hzsB (kuste2859)
Hydrazine synthase subunit beta
Kuenenia stuttgartiensis
Reviewed
CT573071 
CAJ73611.1
Q1Q0T4
Gene
Protein name
Organism
Status
Accession Number (Genbank)
Accession Number (GenPept)
Accession Number (UniProt)
hzsC (kuste2860)
Hydrazine synthase subunit gamma
Kuenenia stuttgartiensis
Reviewed
CT573071 
CAJ73612.1
Q1Q0T3
Reference

Authors

Title

PubMed ID

Full research link

van Niftrikand Jetten. 2012

Anaerobic ammonium-oxidizing bacteria: unique microorganisms with exceptional properties

22933561

Link

Authors

Title


PubMed ID

Full research link

Harhangi et al., 2012

Hydrazine synthase, a unique phylomarker with which to study the presence and biodiversity of anammox bacteria

22138989

Link

Authors

Title


PubMed ID

Full research link

Yang et al., 2018

Two identical copies of the hydrazine synthase gene clusters found in the genomes of anammox bacteria

n/a

Link

Authors

Title

PubMed ID

Full research link

Kartal et al., 2011

Molecular mechanism of anaerobic ammonium oxidation

21964329

Link

Authors

Title

PubMed ID

Full research link

Dietl et al., 2015

The inner workings of the hydrazine synthase multiprotein complex

26479033

Link

Authors

Title

PubMed ID

Full research link

Karlsson et al., 2009

Identification of key proteins involved in the anammox reaction

19558586

Link

Authors

Title

PubMed ID

Full research link

Kartal et al., 2013

How to make a living from anaerobic ammonium oxidation

23210799

Link