AL123456.3

Detailed information

Microorganism
Mycobacterium tuberculosis H37Rv

Taxonomy
Phylum : Actinobacteria Class : nan Order : Corynebacteriales Family : Mycobacteriaceae Genus : Mycobacterium

Isolation Source
nan

Enzyme Name
Probable respiratory nitrate reductase (gamma chain) NarI

Protein Information
Pro_GenBank I.D： CCP43920.1 Length：246 aa Protein FASTA_sequence: Link

Information about Article
Reference：Cole et al., 1998 Title：Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence Pubmed ID：9634230.0 Pubmed link： Link Full research link： Link Abstract：Countless millions of people have died from tuberculosis, a chronic infectious disease caused by the tubercle bacillus. The complete genome sequence of the best-characterized strain of Mycobacterium tuberculosis, H37Rv, has been determined and analysed in order to improve our understanding of the biology of this slow-growing pathogen and to help the conception of new prophylactic and therapeutic interventions. The genome comprises 4,411,529 base pairs, contains around 4,000 genes, and has a very high guanine + cytosine content that is reflected in the biased amino-acid content of the proteins. M. tuberculosis differs radically from other bacteria in that a very large portion of its coding capacity is devoted to the production of enzymes involved in lipogenesis and lipolysis, and to two new families of glycine-rich proteins with a repetitive structure that may represent a source of antigenic variation.

Reference：Cole et al., 1998
Title：Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
Pubmed ID：9634230.0
Pubmed link： Link
Full research link： Link
Abstract：Countless millions of people have died from tuberculosis, a chronic infectious disease caused by the tubercle bacillus. The complete genome sequence of the best-characterized strain of Mycobacterium tuberculosis, H37Rv, has been determined and analysed in order to improve our understanding of the biology of this slow-growing pathogen and to help the conception of new prophylactic and therapeutic interventions. The genome comprises 4,411,529 base pairs, contains around 4,000 genes, and has a very high guanine + cytosine content that is reflected in the biased amino-acid content of the proteins. M. tuberculosis differs radically from other bacteria in that a very large portion of its coding capacity is devoted to the production of enzymes involved in lipogenesis and lipolysis, and to two new families of glycine-rich proteins with a repetitive structure that may represent a source of antigenic variation.