Biological Nitrogen Removal Database

A manually curated data resource for microbial nitrogen removal


Detailed description of the enzyme

Enzyme name Periplasmic nitrate reductase (cytochrome)
Synonyms nitrate reductase, periplasmic;
NapA;
NapAB;
NAP enzyme;
Reductase, nitrate (cytochrome);
NapDAGHB;
NapABC;
Nitrate reductase (cytochrome);
Classification Oxidoreductases
Genes napA, napB, napC, napD
Pathway Nitrogen metabolism: Denitrification: Nitrate reduction
Substrate Nitrate 
Ferrocytochrome c
 Hydron
Product Nitrite 
Ferricytochrome c
Mechanism Link
Subunit
Gene
Protein name
Organism
Status
Accession Number (Genbank)
Accession Number (GenPept)
Accession Number (UniProt)
 napA
Periplasmic nitrate reductase
Escherichia coli strain K12
Reviewed
AP009048 
BAA15989.2
P33937
Gene
Protein name
Organism
Status
Accession Number (Genbank)
Accession Number (GenPept)
Accession Number (UniProt)
 napB
Periplasmic nitrate reductase, electron transfer subunit
Escherichia coli strain K12
Reviewed
AP009048 
BAE76666.1
P0ABL3
Gene
Protein name
Organism
Status
Accession Number (Genbank)
Accession Number (GenPept)
Accession Number (UniProt)
 napC
Cytochrome c-type protein NapC
Escherichia coli strain K12
Reviewed
AP009048 
BAE76665.1
P0ABL5
Gene
Protein name
Organism
Status
Accession Number (Genbank)
Accession Number (GenPept)
Accession Number (UniProt)
 napD
Chaperone NapD
Escherichia coli strain K12
Reviewed
AP009048 
BAA15990.1
P0A9I5
Reference

Authors

Title


PubMed ID

Full research link

Potter and Cole. 1999

Essential roles for the products of the napABCD genes,
but not napFGH, in periplasmic nitrate reduction by Escherichia coli K-12

10548535

Link

Authors

Title


PubMed ID

Full research link

Mintmier et al., 2018

Molecular Cloning, Expression and Biochemical
Characterization of Periplasmic Nitrate Reductase From Campylobacter Jejuni

29931366

Link

Authors

Title


PubMed ID

Full research link

Dementin et al., 2007

Access to the Active Site of Periplasmic Nitrate Reductase:
Insights From Site-Directed Mutagenesis and Zinc Inhibition Studies

17676770

Link

Authors

Title

PubMed ID

Full research link

Coelho and Romão., 2015

Structural and Mechanistic Insights on Nitrate Reductases

26362109

Link

Authors

Title


PubMed ID

Full research link

Dow et al., 2014

Characterization of a Periplasmic Nitrate Reductase
in Complex With Its Biosynthetic Chaperone

24314029

Link

Authors

Title

PubMed ID

Full research link

Grant and Hochstein, 1984

A Dissimilatory Nitrite Reductase in Paracoccus Halodenitrificans

6712419

Link


Biological Nitrogen Removal Database